Le Su Selected Research

phosphatidylcholine-specific phospholipase C

1/2020	Discovery of novel PC-PLC activity inhibitors.
10/2013	Phosphatidylethanolamine binding protein 1 in vacular endothelial cell autophagy and atherosclerosis.
6/2011	Lipopolysaccharide activated phosphatidylcholine-specific phospholipase C and induced IL-8 and MCP-1 production in vascular endothelial cells.
3/2010	D609 inhibits progression of preexisting atheroma and promotes lesion stability in apolipoprotein e-/- mice: a role of phosphatidylcholine-specific phospholipase in atherosclerosis.

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Le Su Research Topics

Disease

13	Neoplasms (Cancer) 06/2022 - 01/2008
5	Inflammation (Inflammations) 06/2022 - 06/2011
4	Carcinogenesis 04/2021 - 03/2012
4	Synovial Sarcoma (Synovioma) 04/2021 - 06/2008
4	Atherosclerotic Plaque (Atheroma) 10/2019 - 03/2010
4	Atherosclerosis 07/2014 - 03/2010
3	Ulcerative Colitis 01/2022 - 10/2021
3	Lung Neoplasms (Lung Cancer) 05/2019 - 01/2017
2	Fibrosis (Cirrhosis) 06/2022 - 01/2014
2	Neoplasm Metastasis (Metastasis) 01/2020 - 01/2018
2	Vascular Diseases (Vascular Disease) 01/2019 - 02/2012
2	Starvation 01/2019 - 02/2016
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 02/2016
2	Hepatocellular Carcinoma (Hepatoma) 09/2017 - 11/2015
1	Intervertebral Disc Displacement (Herniated Disc) 06/2022
1	Weight Loss (Weight Reduction) 01/2022
1	Colitis 01/2022
1	Diarrhea 01/2022
1	Arteriosclerosis 01/2021
1	Fatty Liver 01/2021
1	Non-alcoholic Fatty Liver Disease 01/2021
1	Liver Diseases (Liver Disease) 01/2021
1	Infections 01/2020
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 04/2019
1	Hemorrhage 04/2019
1	Ischemic Stroke 01/2019
1	Prostatic Neoplasms (Prostate Cancer) 01/2018
1	Muscular Dystrophies (Muscular Dystrophy) 01/2018
1	Leukemia 01/2017
1	Breast Neoplasms (Breast Cancer) 01/2017
1	Bone Resorption 01/2017
1	Osteoporosis 01/2017
1	Carcinoma (Carcinomatosis) 03/2016
1	Alcoholic Liver Diseases (Alcoholic Liver Disease) 11/2015
1	Sarcoma (Soft Tissue Sarcoma) 02/2014

Drug/Important Bio-Agent (IBA)

5	Apolipoproteins E (ApoE)IBA 01/2021 - 02/2013
5	ApolipoproteinsIBA 10/2019 - 03/2010
4	phosphatidylcholine-specific phospholipase CIBA 01/2020 - 03/2010
4	Pharmaceutical PreparationsIBA 01/2019 - 02/2012
3	Dextran SulfateIBA 01/2022 - 10/2021
3	Oncogene Proteins (Oncogene Protein)IBA 04/2021 - 03/2012
3	Long Noncoding RNAIBA 10/2019 - 01/2015
3	Histone Deacetylases (Histone Deacetylase)IBA 03/2019 - 06/2008
3	Proteins (Proteins, Gene)FDA Link 01/2015 - 06/2008
3	LipopolysaccharidesIBA 01/2015 - 06/2011
3	tricyclodecane-9-yl-xanthogenateIBA 10/2013 - 03/2010
2	CytokinesIBA 01/2022 - 06/2011
2	Ligases (Synthetase)IBA 04/2021 - 03/2019
2	UbiquitinIBA 04/2021 - 03/2019
2	Biological ProductsIBA 01/2020 - 02/2018
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 05/2019 - 01/2009
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2019 - 02/2016
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2018 - 02/2011
2	MicroRNAs (MicroRNA)IBA 11/2015 - 01/2015
2	oxidized low density lipoproteinIBA 01/2015 - 07/2014
2	Histone Deacetylase InhibitorsIBA 01/2009 - 06/2008
1	Plant Growth Regulators (Plant Hormones)IBA 06/2022
1	BrassinosteroidsIBA 06/2022
1	Antineoplastic Agents (Antineoplastics)IBA 06/2022
1	Interleukin-6 (Interleukin 6)IBA 01/2022
1	OccludinIBA 01/2022
1	SmokeIBA 01/2022
1	AerosolsIBA 01/2022
1	OligosaccharidesIBA 01/2022
1	Histone Deacetylase 2IBA 04/2021
1	Therapeutic UsesIBA 04/2021
1	CholesterolIBA 01/2021
1	Threonine (L-Threonine)FDA Link 01/2021
1	Serine (L-Serine)FDA Link 01/2021
1	Benzoic Acid (Potassium Benzoate)FDA Link 05/2019
1	Inosine Triphosphate (ITP)IBA 04/2019
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	Histones (Histone)IBA 01/2019
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019
1	histone H3 trimethyl Lys4IBA 01/2019
1	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA 01/2019
1	Glutathione (Reduced Glutathione)IBA 01/2018
1	Annexin A7 (Synexin)IBA 01/2018
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2018
1	GTP Phosphohydrolases (GTPases)IBA 01/2018
1	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 09/2017
1	CalciumIBA 01/2017
1	Chalcone (Benzalacetophenone)IBA 01/2017
1	Aromatase InhibitorsIBA 01/2017
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2017
1	Estrogen ReceptorsIBA 01/2017
1	Alendronate (Alendronate Sodium)FDA LinkGeneric 01/2017
1	bushen jianpiIBA 01/2017
1	Phosphorus (Red Phosphorus)IBA 01/2017
1	Alkaline PhosphataseIBA 01/2017
1	IntegrinsIBA 03/2016
1	hydroxide ionIBA 02/2015
1	ChromatinIBA 02/2014
1	TransducinIBA 02/2014
1	Activating Transcription Factor 2IBA 02/2014
1	Transcription Factors (Transcription Factor)IBA 02/2014
1	Co-Repressor ProteinsIBA 02/2014

Therapy/Procedure

12	Therapeutics 01/2020 - 01/2009
1	Laminectomy 06/2022
1	Transplantation 01/2018